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Engineering Polymer Systems for Improved Drug Delivery

Engineering Polymer Systems for Improved Drug Delivery PDF Author: Rebecca A. Bader
Publisher: John Wiley & Sons
ISBN: 1118747801
Category : Social Science
Languages : en
Pages : 496
Book Description
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Engineering Polymer Systems for Improved Drug Delivery

Engineering Polymer Systems for Improved Drug Delivery PDF Author: Rebecca A. Bader
Publisher: John Wiley & Sons
ISBN: 1118747801
Category : Social Science
Languages : en
Pages : 496
Book Description
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Fundamentals of Drug Delivery

Fundamentals of Drug Delivery PDF Author: Heather A. E. Benson
Publisher: John Wiley & Sons
ISBN: 1119769604
Category : Medical
Languages : en
Pages : 580
Book Description
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery

Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery PDF Author: Zhongwei Gu
Publisher: John Wiley & Sons
ISBN: 3527334203
Category : Medical
Languages : en
Pages : 362
Book Description
Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

Engineering Drug Delivery Systems

Engineering Drug Delivery Systems PDF Author: Ali Seyfoddin
Publisher: Woodhead Publishing
ISBN: 0081025491
Category : Medical
Languages : en
Pages : 250
Book Description
Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Strategies to Modify the Drug Release from Pharmaceutical Systems

Strategies to Modify the Drug Release from Pharmaceutical Systems PDF Author: Marcos Luciano Bruschi
Publisher: Woodhead Publishing
ISBN: 0081001126
Category : Medical
Languages : en
Pages : 208
Book Description
Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Biodegradable and Biocompatible Polymer Composites

Biodegradable and Biocompatible Polymer Composites PDF Author: Navinchandra Gopal Shimpi
Publisher: Woodhead Publishing
ISBN: 0081010583
Category : Technology & Engineering
Languages : en
Pages : 438
Book Description
Biodegradable and Biocompatible Polymer Composites: Processing, Properties and Applications begins by discussing the current state-of-the-art, new challenges and opportunities for various biodegradable and biocompatible polymer composite systems. Interfacial characterization of composites and the structure-property relationships in various composite systems are explained in detail via a theoretical model. Processing techniques for various macro and nanocomposite systems and the influence of processing parameters on properties of the composite are also reviewed in detail. The characterization of microstructure, elastic, visco-elastic, static and dynamic mechanical, thermal, rheological, optical, and electrical properties are highlighted, as are a broad range of applications. The book is a useful reference resource for both researchers and engineers working in composites materials science, biotechnology and nanotechnology, and is also useful for students attending chemistry, physics, and materials science and engineering courses. Presents recent outcomes and highlights the going importance of biodegradable and biocompatible polymer composites and their impact on the environment Analyzes all the main processing techniques, characterization and applications of biodegradable composites Written by leading international experts working in the field of biodegradable and biocompatible polymer composites Covers a broad range of application fields, including medical and pharmaceutical, agricultural, packaging and transport

Smart Polymers

Smart Polymers PDF Author: José Miguel García
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 1501522469
Category : Technology & Engineering
Languages : en
Pages : 153
Book Description
Smart polymers react sharply to small changes in physical or chemical conditions and present an intelligent response to chemical stimuli (i.e., chemical species -including biomolecules-, pH, solvents, redox, stimuli that trigger controlled depolymerization) and physical stimuli (i.e., temperature, light, mechanical stress and electrical stimuli). For these reasons, the interest in smart polymers has recently increased exponentially, especially in biological stimuli (i.e., application of polymer-based biosensors, drug delivery, tissue engineering, precision medicine and cell therapy). This book offers a unique opportunity to review the physical-chemical fundamentals of smart polymers, and their behaviour. It also provides an excellent review of the main applications of smart polymers.

Polymer Nanoparticles for Nanomedicines

Polymer Nanoparticles for Nanomedicines PDF Author: Christine Vauthier
Publisher: Springer
ISBN: 3319414216
Category : Medical
Languages : en
Pages : 641
Book Description
This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

Localized Micro/Nanocarriers for Programmed and On-Demand Controlled Drug Release

Localized Micro/Nanocarriers for Programmed and On-Demand Controlled Drug Release PDF Author: Seyed Morteza Naghib
Publisher: Bentham Science Publishers
ISBN: 9815051644
Category : Medical
Languages : en
Pages : 266
Book Description
This book provides a comprehensive overview of the localized drug delivery system landscape. The 10 chapters provide a detailed introduction in polymers, nanostructures and nanocomposites for developing localized controlled drug delivery systems (LCDDSs) in the form of stimuli-responsive delivery systems, targeted drug delivery systems or the combination of both. A discussion on manufacturing techniques, optimization, challenges and adaptation of LCDDSs for the treatment of a wide range of diseases is also included. This simple and informative resource conveys an understanding about designing novel drug delivery systems to students in advanced pharmacology, biotechnology, materials science and biochemistry study programs. Readers will be equipped with the knowledge of regulating drug release rates to get a desired pharmacological profile, that helps a researcher to ensure a high therapeutic effectiveness. The detailed information about various drug delivery systems and a compilation of recent literature sources also paves the way for research scholars to construct a drug targeting framework for their research plans.

Biomaterials Science

Biomaterials Science PDF Author: William R Wagner
Publisher: Academic Press
ISBN: 0128161388
Category : Medical
Languages : en
Pages : 1616
Book Description
The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters