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Motor Neuron Disease Research Progress

Motor Neuron Disease Research Progress PDF Author: Raffaele L. Mancini
Publisher: Nova Publishers
ISBN: 9781604561555
Category : Medical
Languages : en
Pages : 330
Book Description
The motor neuron diseases (or motor neuron diseases) (MND) are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. Signs of upper motor neuron damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neuron damage include weakness and muscle atrophy. Every muscle group in the body requires both upper and lower motor neurons to function. It is a common misconception that "upper" motor neurons control the arms, while "lower" motor neurons control the legs. The signs described above can occur in any muscle group, including the arms, legs, torso, and bulbar region. Symptoms usually present between the ages of 50-70, and include progressive weakness, muscle wasting, and muscle fasciculations; spasticity or stiffness in the arms and legs; and overactive tendon reflexes. Patients may present with symptoms as diverse as a dragging foot, unilateral muscle wasting in the hands, or slurred speech. This new book presents the latest research from around the globe.

Motor Neuron Disease Research Progress

Motor Neuron Disease Research Progress PDF Author: Raffaele L. Mancini
Publisher: Nova Publishers
ISBN: 9781604561555
Category : Medical
Languages : en
Pages : 330
Book Description
The motor neuron diseases (or motor neuron diseases) (MND) are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. Signs of upper motor neuron damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neuron damage include weakness and muscle atrophy. Every muscle group in the body requires both upper and lower motor neurons to function. It is a common misconception that "upper" motor neurons control the arms, while "lower" motor neurons control the legs. The signs described above can occur in any muscle group, including the arms, legs, torso, and bulbar region. Symptoms usually present between the ages of 50-70, and include progressive weakness, muscle wasting, and muscle fasciculations; spasticity or stiffness in the arms and legs; and overactive tendon reflexes. Patients may present with symptoms as diverse as a dragging foot, unilateral muscle wasting in the hands, or slurred speech. This new book presents the latest research from around the globe.

Research Progress in Motor Neurone Disease

Research Progress in Motor Neurone Disease PDF Author: Frank Clifford Rose
Publisher:
ISBN:
Category : Amyotrophic lateral sclerosis
Languages : en
Pages : 488
Book Description


Research Progress in Alzheimer's Disease and Dementia

Research Progress in Alzheimer's Disease and Dementia PDF Author: Miao-Kun Sun
Publisher: Nova Publishers
ISBN: 9781600219603
Category : Medical
Languages : en
Pages : 452
Book Description
Alzheimer's disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective treatments are developed. Since the publication of the second book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide. This third book volume contains 15 chapters, bringing together a presentation of research frontiers in current AD/dementia research. The topics include molecular genetics of AD, gene expression abnormalities in AD progression, presenilins, taupathy in AD, single -induced(neuron gene expression abnormalities in AD, intracellular A neurodegeneration, roles of lipoprotein receptors in AD onset and progression, cholesterol and tau hyperphosphorylation, AD diagnostics and therapeutic strategies, in vivo visualisation of amyloid-like structures, cathepsin B, antiamyloidogenesis and neuroprotection, environmental enrichment, Fragile X mental retardation gene and dementia, category learning in Parkinson's disease, cerebrovascular disease and dementia, and dementia and hypertension. These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research progress in AD and dementia.

Motor Neuron Disease

Motor Neuron Disease PDF Author: P.N. Leigh
Publisher: Springer Science & Business Media
ISBN: 1447118715
Category : Medical
Languages : en
Pages : 468
Book Description
Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Animal Biotechnology

Animal Biotechnology PDF Author: Ashish S. Verma
Publisher: Academic Press
ISBN: 0128117257
Category : Medical
Languages : en
Pages : 798
Book Description
Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Contributions to Contemporary Neurology

Contributions to Contemporary Neurology PDF Author: Robert B. Daroff
Publisher: Butterworth-Heinemann
ISBN: 1483192628
Category : Health & Fitness
Languages : en
Pages : 278
Book Description
Contributions to Contemporary Neurology features articles presented at the scientific meeting at the March 1986 gala evening affair held in Cleveland, Ohio in honor of neurologist Joseph Michael Foley's seventieth birthday and his impending transition to Professor Emeritus at Case Western University. This book is organized into 20 chapters written by 41 contributors. It starts with the biography of Foley and ends with his curriculum vitae. In between the biographies and curriculum vitae are basic and clinical articles written by professionals closely associated with Foley throughout his illustrious career. This book will be of interest to those interested in learning about the life and career of neurologist Joseph Michael Foley.

250 Cases in Clinical Medicine E-Book

250 Cases in Clinical Medicine E-Book PDF Author: Ragavendra R. Baliga
Publisher: Elsevier Health Sciences
ISBN: 0702050261
Category : Medical
Languages : en
Pages : 929
Book Description
A new, fully updated edition of Baliga's very popular collection of short cases arranged by clinical area, emphasising the key diagnostic features of clinical conditions as commonly presented in the short-case part of the Final MB and MRCP examinations. Also included are likely instructions or commands expected from the examiner for each condition, and the key points which the candidate must tell the examiner. A must-have for the final-year undergraduate and trainee doctor. From customer reviews of the previous edition: 'This book is the most useful guide that money can buy for the final exams in the current MBChB undergraduate course. It covers important areas of clinical medicine in a question based format and highlights classical scenarios. The questions raised are classical of examiners in the long and short case examinations. This is a must buy for any undergraduate medical student!!!' 'The book is a must during the period that the young doctor or student is on the wards. It allows one to focus on the important physical findings and the relavant clinical pearls associated with the different medical conditions met... It discusses important physical findings and their diagnostic importance. I have found it useful in preparing for attending ward rounds and also for sharpening my clinical skills. The discussion section is well organised such that undergraduates as well as postgraduates can benefit and the material is up to date with good references for further reading.' 'Excellent preparation for finals as well the MRCP ...MUST HAVE before MRCP PACES.' Features Ideal for use in the ward. Each of the 250 cases presents a disease or topic which is covered consistently to address:● salient features ● history ● examination ● diagnosis ● questions covering investigations and differentiations ● advanced-level questions ● management. New to this edition: Over 350 new images Enhanced advanced-level questions Many more tables

Gangliosides and Neuronal Plasticity

Gangliosides and Neuronal Plasticity PDF Author: G. Tettamanti
Publisher: Springer Science & Business Media
ISBN: 1475753098
Category : Medical
Languages : en
Pages : 483
Book Description
This volume contains the Proceedings of the Meeting "Neuronal plasticity and gangliosides" which was held at Mantova, Italy, on May 29-31, 1985, as a satellite to the Tenth Meeting of the International Society for Neurochemistry, (Riva del Garda, Italy, May 19-24,1985). The Symposium took place in the "Teatro Bibiena", one of the oldest and most beautiful theatres in Italy, known for having been the place for some of the very first performances of W .A. Mozart. The number of registered participants in the Meeting was about 180 including 40 accor:Qpanying persons. The persons invited as Speakers or Chairmen of Colloquia and Workshops were 48. Eighteen countries were represented with the largest contingent coming from Italy, followed by Federal Republic of Germany, The United States, France and Great Britain. The Meeting was based on Colloquia, Workshops, Round Tables and Poster Sessions, with a total of 42 Lectures and 32 Poster presentations.

Clinical Cases & Pearls in Medicine

Clinical Cases & Pearls in Medicine PDF Author: GS Sainani
Publisher: JP Medical Ltd
ISBN: 9351526461
Category : Medical
Languages : en
Pages : 474
Book Description
This book has been written with an aim to facilitate students preparing for medicine practical at final MBBS, MD, DNB, FCPS and MRCP examinations. The author discusses 203 clinical cases and 101 pearls in medicine. Pearls are nothing but important messages of clinical medicine which will help students to face the viva voce during practical examinat

Neuromuscular Diseases

Neuromuscular Diseases PDF Author: Michael Swash
Publisher: Springer Science & Business Media
ISBN: 1447138341
Category : Medical
Languages : en
Pages : 541
Book Description
Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.