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Molecular Mechanisms of Parasite Invasion

Molecular Mechanisms of Parasite Invasion PDF Author: Barbara A. Burleigh
Publisher: Springer Science & Business Media
ISBN: 0387782672
Category : Medical
Languages : en
Pages : 237
Book Description
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

Molecular Mechanisms of Parasite Invasion

Molecular Mechanisms of Parasite Invasion PDF Author: Barbara A. Burleigh
Publisher: Springer Science & Business Media
ISBN: 0387782672
Category : Medical
Languages : en
Pages : 237
Book Description
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

Invasion Genetics

Invasion Genetics PDF Author: Spencer C. H. Barrett
Publisher: John Wiley & Sons
ISBN: 1118922182
Category : Science
Languages : en
Pages : 400
Book Description
Invasion Genetics: the Baker & Stebbins legacy provides a state-of-the-art treatment of the evolutionary biology of invasive species, whilst also revisiting the historical legacy of one of the most important books in evolutionary biology: The Genetics of Colonizing Species, published in 1965 and edited by Herbert Baker and G. Ledyard Stebbins. This volume covers a range of topics concerned with the evolutionary biology of invasion including: phylogeography and the reconstruction of invasion history; demographic genetics; the role of stochastic forces in the invasion process; the contemporary evolution of local adaptation; the significance of epigenetics and transgenerational plasticity for invasive species; the genomic consequences of colonization; the search for invasion genes; and the comparative biology of invasive species. A wide diversity of invasive organisms are discussed including plants, animals, fungi and microbes.

Minimal Neoplasia

Minimal Neoplasia PDF Author: Ekkehard Grundmann
Publisher: Springer Science & Business Media
ISBN: 3642832458
Category : Medical
Languages : en
Pages : 194
Book Description
Minimal neoplasia may be defined as a small cancer that has progressed beyond its site of primary origin into the surrounding tissue, but that has not yet reached the stage of deeper invasion or metastasization. The basic principles of this minimal cancer are presented in chapters on molecular, biological and experimental aspects, and, in particular, on the clinical manifestations in various organs: preleukemia, incipient lymphoma, and minimal carcinomas of the uterine cervix, breast, thyroid, larynx, lung, prostate, stomach and colon. A separate chapter is devoted to cryptic gliomas. The latest morphological methods including cytology, early clinical diagnostics and, in particular, radiodiagnostics, are considered. The reader can expect up-to-date information about prompt diagnosis of the very early manifestations of cancer, together with inferences on therapy, which, especially in tumors of the uterine cervix, breast and thyroid, differs considerably from the treatment of advanced neoplasia.

Mie Medical Journal

Mie Medical Journal PDF Author:
Publisher:
ISBN:
Category : Medical sciences
Languages : en
Pages :
Book Description


Salmonella Infections

Salmonella Infections PDF Author: Pietro Mastroeni
Publisher: Cambridge University Press
ISBN: 9780521835046
Category : Medical
Languages : en
Pages : 410
Book Description
Integrated view of clinical, molecular and immunological aspects of the biology of Salmonella enterica infections.

Molecular Strategies of Parasitic Invasion

Molecular Strategies of Parasitic Invasion PDF Author: Nina Agabian
Publisher: Alan R. Liss
ISBN:
Category : Biologie moléculaire - Congrès
Languages : en
Pages : 822
Book Description


Feigin and Cherry's Textbook of Pediatric Infectious Diseases E-Book

Feigin and Cherry's Textbook of Pediatric Infectious Diseases E-Book PDF Author: James Cherry
Publisher: Elsevier Health Sciences
ISBN: 0323186602
Category : Medical
Languages : en
Pages : 3200
Book Description
Feigin and Cherry's Textbook of Pediatric Infectious Diseases helps you put the very latest knowledge to work for your young patients with unparalleled coverage of everything from epidemiology, public health, and preventive medicine through clinical manifestations, diagnosis, treatment, and much more. Ideal for all physicians, whether in an office or hospital setting, Feigin and Cherry’s equips you with trusted answers to your most challenging clinical infectious disease questions. Meet your most difficult clinical challenges in pediatric infectious disease, including today’s more aggressive infectious and resistant strains as well as emerging and re-emerging diseases, with unmatched, comprehensive coverage of immunology, epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. Find the answers you need quickly thanks to an organization both by organ system and by etiologic microorganism, allowing you to easily approach any topic from either direction.

Molecular Pathology in Cancer Research

Molecular Pathology in Cancer Research PDF Author: Sunil R. Lakhani
Publisher: Springer
ISBN: 149396643X
Category : Medical
Languages : en
Pages : 369
Book Description
The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.

Biomedical Index to PHS-supported Research

Biomedical Index to PHS-supported Research PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 912
Book Description


The Molecular Basis of Cancer

The Molecular Basis of Cancer PDF Author: John Mendelsohn
Publisher: W B Saunders Company
ISBN:
Category : Medical
Languages : en
Pages : 728
Book Description
The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating the latest advances and newest research, this text also gives thorough descriptions of everything from the basic mechanisms of malignant cells and molecular abnormalities in common cancers to new approaches for cancer therapy. Each chapter discusses the clinical implications for treatment. Numerous examples of the latest clinical interventions help readers understand and assess the products of the biotechnology revolution. IMPORTANT new topics, including chemo-prevention, programmed cell death (apoptosis), genetic counselling, tumour-specific vaccines, genetic abnormalities in the origin and progression of cancer, monoclonal antibody therapy, and molecular predictors of prognosis and response to treatment NEW and revised chapters, covering new basic science knowledge, new approaches to treatment and keeping all information on the cutting-edge of the specialty ABUNDANT illustrations, most of them new, to clarify and explain difficult concepts.